liver cirrhosis
Conditions
Interventions
Acute decompensation group:None
Progressive decompensation group:None
Subclinical decompensation group:None
Sponsors
Beijing Ditan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old; 2. Patients diagnosed with decompensated cirrhosis according to the Guidelines for the Diagnosis and Treatment of Liver Cirrhosis issued by the Hepatology Section of the Chinese Medical Association in 2019; 3. Prospective enrollment and follow-up patients voluntarily participated and signed an informed consent form.
Exclusion criteria
Exclusion criteria: Patients were excluded if they met any of the following exclusion criteria 1. Patients with diagnosis of primary hepatocellular carcinoma; 2. Previous history of nephrotic syndrome, or serum creatinine (Cr) >2 × ULN, or Cr elevation >50 µmol/L or more during the screening period; urinary protein 2+ and above; 3. Combination of other serious diseases, including but not limited to malignant tumor, non-cirrhotic portal hypertension ascites, ischemic heart disease, stroke, chronic obstructive pulmonary disease, and class III-IV heart failure; 4. Organ transplant recipients; 5. Poor patient compliance and inability to complete the visit requirements; 6. Patients whom the investigator considers unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative mortality associated with liver disease in patients with different patterns of decompensated cirrhosis.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of cirrhosis-related complications, liver failure, liver transplantation and primary liver cancer in patients with different patterns of decompensated cirrhosis;Risk factors for liver disease-related mortality in patients with decompensated cirrhosis; Predictive value of a risk prediction model for decompensated cirrhosis;Incidence of recompensation in decompensated cirrhosis; | — |
Countries
China
Contacts
Public ContactQi Wang
Center of Liver Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China
Outcome results
None listed