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Clinical observation of bilateral lumbar plexus nerve block after laparoscopic total hysterectomy using bupivacaine liposomes and levobupivacaine hydrochloride

Clinical observation of bilateral lumbar plexus nerve block after laparoscopic total hysterectomy using bupivacaine liposomes and levobupivacaine hydrochloride

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097716
Enrollment
Unknown
Registered
2025-02-25
Start date
2025-03-10
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine diseases

Interventions

A: Bupivacaine liposome group :For patients undergoing laparoscopic transabdominal total hysterectomy, after general anesthesia with endotracheal intubation, Group A: 20ml (266mg) of bupivacaine li
B: levobupivacaine hydrochloride group:For patients undergoing laparoscopic transabdominal total hysterectomy, after general anesthesia with endotracheal intubation, Group B received bilateral lumbar

Sponsors

The Second Affiliated Hospital of Hainan Medical College
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Age: 18-70 years old, Body Mass Index (BMI): 18-30kg/m2; (2) American Society of Anesthesiologists (ASA) classification: I-III; (3) No concurrent heart, liver, or kidney diseases; (4) The patient plans to undergo laparoscopic transabdominal total hysterectomy; (5) Normal coagulation function and platelet function; (6) <3 hours during surgery; (7) The patient or family agrees and signs an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Individuals allergic to bupivacaine; (2) Infection at the puncture site is not suitable for nerve block operators; (3) Opioid addicts; (4) Patients with severe consciousness disorders or those with mental and cognitive impairments. (5) Patients with combined heart, liver, kidney diseases, and coagulation dysfunction.

Design outcomes

Primary

MeasureTime frame
VAS pain score;First analgesia pump compression time;Number of compressions of analgesic pump;The usage of opioid drugs;Duration of continuous analgesia;

Secondary

MeasureTime frame
Nauseated;Vomiting;Dizzy;Headache;Hypersomnia;Hypotension;Hypertension;Lower limb muscle strength;

Countries

China

Contacts

Public ContactWei Xuemei

The Second Affiliated Hospital of Hainan Medical College

13807683589@163.com+86 138 0768 3589

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026