Preoperative anxiety patients undergoing total knee arthroplasty
Conditions
Interventions
taVNS group:The transauricular vagus nerve electrical stimulation electrode was placed on the patients ear concha for stimulation treatment
staVNS group:The transauricular vagus nerve electrical stimulation electrode was placed on the patients auricle for sham stimulation
Sponsors
The Second Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. aged 18-65 years; 2. ASA class i~iii; 3. patients undergoing elective knee arthroplasty; 4. preoperative anxiety (SAS score greater than 50); 5. voluntarily participate in the trial and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. preoperative arrhythmia (bradycardia, atrioventricular block, etc.); 2. there are damages, redness, swelling, infection, etc. on the skin at the vagus nerve site of ear electrical stimulation; 3. those suffering from infectious diseases, malignant tumors, serious hematopoietic system diseases and those with serious diseases such as heart, brain, liver and kidney; 4. patients with mental illness or preoperative cognitive dysfunction; 5. patients who take psychotropic drugs or opioids for a long time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery, QoR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Infrared thermal imaging inspection data;Perioperative adverse events (hypotension, bradycardia, nausea and vomiting, etc.;Richards-Campbell Sleep Questionnaire, RCSQ;Zung Self-Rating Anxiety Scale; | — |
Countries
China
Contacts
Public ContactXinlei Zhang
The Second Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed