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Efficacy of a new local anesthetic bupivacaine liposome pudendal nerve block in postoperative hemorrhoidal analgesia: a double-blind randomized controlled trial

Efficacy of a new local anesthetic bupivacaine liposome pudendal nerve block in postoperative hemorrhoidal analgesia: a double-blind randomized controlled trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097701
Enrollment
Unknown
Registered
2025-02-24
Start date
2025-02-26
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haemorrhoids

Interventions

Control group:Under the guidance of ultrasound, 0.375% ropivacaine 10ml was injected into the pudendal nerve on both sides
Experimental group:Under ultrasound guidance, 1.33% bupivacaine liposomes (20ml
266mg) 10ml block

Sponsors

Affiliated Hospital of Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Patients with hemorrhoids undergoing mixed hemorrhoidal external stripping and internal ligation; (2) Age 18~65 years old.

Exclusion criteria

Exclusion criteria: (1) Severe visceral organ lesions, tumors and abnormal coagulation function cannot be treated with subarachnoid anesthesia; (2) pregnant and lactating women; (3) mental illness; (4) is participating in other investigational studies or treatments; (5) In addition to the pain induced by mixed hemorrhoids, it is accompanied by pain induced by other causes; (6) Abnormalities of inflammatory factors caused by physical factors, chemical factors, foreign bodies, necrotic tissues and allergic reactions.

Design outcomes

Primary

MeasureTime frame
Pain score and incidence of mild, moderate and severe pain;

Secondary

MeasureTime frame
Inflammatory factors;

Countries

China

Contacts

Public ContactZhan Wei

Affiliated Hospital of Guizhou Medical University

16799507@qq.com+86 138 8502 3122

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026