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The Effect of Transcutaneous Vagus Nerve Stimulation on Postoperative Pulmonary Complications and Early Recovery Quality in Elderly Patients Undergoing Thoracoscopic Lobectomy

The Effect of Transcutaneous Vagus Nerve Stimulation on Postoperative Pulmonary Complications and Early Recovery Quality in Elderly Patients Undergoing Thoracoscopic Lobectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097638
Enrollment
Unknown
Registered
2025-02-24
Start date
2025-02-26
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary complications (PPCs)

Interventions

Postoperative day 1 2. Stimulation Parameters:Pulse width: 200 µs
Frequency: 30 Hz
Current intensity:Initial ramp-up from 10 mA to a noxious threshold (defined as participant-reported "tingling/pain" within 20 seconds)
Subsequent adjustment to sub-threshold current levels (20–60 mA)
Postoperative day 1 2. Apply sham stimulation for 30 minutes each session: abort stimulation if the participant reports "tingling/pain"

Sponsors

The Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >=60 years old 2.Patients undergoing Thoracoscopic Lobectomy 3.ASA grade I-III 4.Those who agree to participate in the experiment and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Preoperative use of radiotherapy, chemotherapy, anti-inflammatory agents, analgesics, or corticosteroids 2. Presence of implanted electronic devices (e.g., pacemakers) 3. Patients with otitis externa or tragal cartilage injury 4. History of prior pulmonary surgery 5. Severe cardiovascular and cerebrovascular diseases, renal insufficiency, or hepatic dysfunction 6. Clinically significant arrhythmias requiring treatment preoperatively 7. History of mechanical ventilation, respiratory failure, or acute respiratory distress syndrome (ARDS) 8. Acute or chronic pain syndromes or hyperalgesia preoperatively 9. Preexisting psychiatric disorders 10. Current dependence on psychotropic drugs, opioids, or alcohol

Design outcomes

Primary

MeasureTime frame
Incidence of Postoperative pulmonary complications;

Secondary

MeasureTime frame
Early Recovery Outcomes;Pain scores;Postoperative inflammatory indicators;Parameters reflecting lung function;Total consumption of opioid drugs;Duration of hospitalization;The number of adverse event case;

Countries

China

Contacts

Public ContactWenjing Zhao

The Affiliated Hospital of Xuzhou Medical University

Zhaowj886@sina.com+86 138 5215 7285

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026