Chronic insomnia
Conditions
Interventions
Healthy control group:None
Sponsors
Chengdu Second People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for CID disorder in the Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5); (2) PSQI score >= 7 points; (3) Symptoms of insomnia lasting more than three months include difficulty falling asleep, not sleeping deeply or waking early; (4) between the age of 18-60 years old, and the education level of >= 9 years (junior high school or above); (5) did not take sleeping drugs or other psychotropic drugs within 2 weeks before enrollment; (6) HAMD score = 26 to exclude cognitive impairment.
Exclusion criteria
Exclusion criteria: (1) History of disturbance of consciousness; (2) a history of other types of sleep disorders, such as sleep apnea, restless leg syndrome, movement during periodic limb sleep, or circadian rhythm sleep disorders (e.g., early sleep syndrome); (3) Current use of drugs known to cause insomnia (such as steroids); (4) Other medical history: such as central nervous system infection, head injury, epilepsy, multiple sclerosis, toxic metabolic diseases, Parkinson's disease, intracranial tumors, diabetes and other physical diseases; History of major depression, bipolar disorder, severe anxiety disorder, schizophrenia, personality change and other mental illness; (5) A history of alcohol, drug, coffee dependence; (6) There are contraindications for MRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain oxygenated hemoglobin concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index;Insomnia Severity Index;Epworth Sleepiness Scale;Hamilton Depression Scale;Hamilton Anxiety Scale;Mini-Mental State Examination;auditory verbal learning test; | — |
Countries
China
Contacts
Public ContactLiang Gong
Chengdu Second People's Hospital
Outcome results
None listed