AIDS
Conditions
Interventions
One:HIV patients who receive national free drug treatment
Two:HIV patients who receive medical insurance drug treatment
Sponsors
The First Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged between 18 and 65 years old. (2) Confirmed to be infected with HIV through the initial screening test and the Western Blot (WB) confirmation test. (3) The viral load detected is lower than the minimum detectable value. (4) The number of CD4+ T cells is greater than 200 cells/mm³. (5) Voluntarily sign the patient informed consent form and be able to ensure acceptance of regular follow-up, specimen collection, and reporting of relevant adverse reactions to treatment. (6) Meeting one of the following conditions: patients aged over 50 years old; late diagnosis; patients with multiple underlying diseases; patients with highly suppressed immunity, such as the CD4+ T lymphocyte count < 50/µL; incomplete immune reconstitution after antiretroviral therapy (ART).
Exclusion criteria
Exclusion criteria: (1) Pregnant or lactating women, or those who plan to become pregnant during the study observation period. (2) Those with poor treatment compliance. (3) Patients with severe underlying diseases of the heart, brain, liver, kidney, etc., with a neutrophil count < 1000/mm³, a platelet count < 75,000/mm³, patients who are allergic to the study drugs or have other treatment contraindications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma human immunodeficiency viral load;CD4+ T cell count;cytokines; | — |
Countries
China
Contacts
Public ContactBiao Zhu
The First Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed