Low Rectal Cancer
Conditions
Interventions
Experimental Group:Study participants underwent elective laparoscopic Total Mesorectal Excision(TME).During the surgery,an auxiliary incision was made at the stoma site,part of the incision was suture
Control Group:Study participants underwent elective laparoscopic Total Mesorectal Excision(TME).During the surgery,a conventional auxiliary incision(midline lower abdomen)was made to remove the tumor
Sponsors
Department of Colorectal Surgery,First Affiliated Hospital of Naval Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Age over 18 years at the time of diagnosis; (2) Preoperative biopsy pathological diagnosis of rectal adenocarcinoma; (3) Underwent MRI evaluation before surgery, and the lower edge of the tumor was not more than 10cm away from the anal margin; (4) Undergo elective laparoscopic TME for colon-rectal anastomosis, and do not detach the colon in the splenic area during the operation; (5) Baseline clinical stage TNM PHASE I.-III: CT1-4N0-2M0 (AJCC-8version); (6) Heart, lung, liver, and kidney function can tolerate surgery; (7) Patients and their families are able to understand and are willing to participate in this clinical study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with intestinal obstruction, intestinal perforation, intestinal bleeding, etc., requiring emergency surgery; 2. Patients whose tumors involve adjacent organs and require combined organ resection; 3. Patients with tumor recurrence or distant metastasis; 4. Patients with multiple colorectal cancers; 5. History of inflammatory bowel disease or familial adenomatous polyposis; 6. Patients who have participated in or are participating in other clinical trials within 4 weeks prior to enrollment; 7. ASA grade greater than grade III 8. Performance status: Karl Fischer score less than or equal to 60, or ECOG score greater than or equal to 2; 9. Hepatic dysfunction with a MELD score greater than 12 points; 10. Have a history of severe mental illness; 11. Pregnant or lactating women; 12. In the opinion of the investigator, the patient is not suitable to participate in the study due to other conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative stoma complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lengths of the two different types of auxiliary incisions;Postoperative pain score;Incidence of postoperative incisional complications;Time to postoperative incision healing;Intra-abdominal adhesion status at the time of stoma reversal surgery; | — |
Countries
China
Contacts
Public ContactZheng Lou
Department of Colorectal Surgery,First Affiliated Hospital of Naval Medical University
Outcome results
None listed