The Influence of fNIRS Neurofeedback Training on Balance, Walking, and Sensorimotor Cortex Activation in Stroke Patients

The Effect of fNIRS-based Neurofeedback Training on Balance Function, Walking Ability, and Sensorimotor Cortex Activation levels in Stroke Patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500097607

Enrollment

Unknown

Registered

2025-02-21

Start date

2025-02-24

Completion date

Unknown

Last updated

2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recovery phase of stroke (within six months of onset)

Interventions

True Feedback Experimental Group:Neurofeedback training based on fNIRS

Sham Feedback Control Group:Neurofeedback training based on fNIRS

Eligibility

Sex/Gender

All

Age

30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Meet the diagnostic criteria for stroke in "Diagnostic Criteria for Cerebrovascular Diseases in China (2019)" , and confirmed by CT or MRI examination; 2.Patient age between 30-75 years old; 3.First episode of stroke; 4.Patients in the recovery phase of stroke, with onset within six months; 5.Right-handed; 6.Capable of independently completing sit-to-stand transfers and walking independently or with assistance for more than 50 meters; 7.Kinesthetic and Visual Imagery Questionnaire (KVIQ-10) score >=25 ; 8.Berg Balance Scale (BBS) score <=45; 9.Successful activation of feedback system imaging before training;

Exclusion criteria

Exclusion criteria: 1.Severe cognitive impairment or aphasia with a MoCA score of less than 10 points; 2.Severe carotid artery stenosis (>90%) or intracranial stenosis (>75%); 3.Attention deficit or unilateral spatial neglect that may interfere with the examination personnel's instructions; 4.Skull defect or post-surgical repair; 5.Severe visual, speech, and hearing impairments; 6.Previous lower limb dysfunction on the affected side that significantly affects walking; 7.Metal implants in the skull; 8.Unstable vital signs; 9.Visual spatial perception disorder; 10.Severe knee pain and patients deemed ineligible for the study by the attending physician.

Design outcomes

Primary

Measure	Time frame
6-Minute Walk Distance;Plantar pressure parameters;10-Meter Walk Test;lower extremity motor function;Change in oxyhemoglobin concentration;Balance function;	—

Secondary

Measure	Time frame
balance motor function;Lateralization Index;3-meter Timed Up and Go (TUG) Test;	—

Countries

China

Contacts

Public ContactTian Feng

Jining No.1 People's Hospital

545938521@qq.com+86 139 5476 5873

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026