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Magnetic resonance imaging study of brain structure and function of pain transmission pathways in patients with trigeminal neuralgia

Magnetic resonance imaging study of brain structure and function of pain transmission pathways in patients with trigeminal neuralgia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500097566
Enrollment
Unknown
Registered
2025-02-20
Start date
2023-03-11
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

trigeminal neuralgia

Interventions

TN group :None
Healthy control group:None

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for TN patients : 1. those with right-handed; those aged between 40 and 70 years old. 2. individuals meeting the International Classification of Headache Disorders criteria 3. those with disease duration exceeding 3 months. Inclusion criteria for healthy control: 1. those with right-handed; those aged between 40 and 70 years old. 2. No vasoactive drugs have been taken in the last three months.

Exclusion criteria

Exclusion criteria: Exclusion criteria for TN patients and healthy controls: 1. individuals with secondary intracranial diseases such as tumors or trauma; 2. those with other headache disorders; 3. those with a history of alcohol or drug abuse; 4. those with contraindications to MRI; 5. those using TN-related medications for at least 24 hours prior to MRI scanning.

Design outcomes

Primary

MeasureTime frame
Cerebral grey cortex thickness;Cerebral white matter fibre tracts;Cerebral Functional Connectivity;

Secondary

MeasureTime frame
Clinical Behavioural;

Countries

China

Contacts

Public ContactBaijintao Sun

Affiliated Hospital of North Sichuan Medical College

sbjt542316334@163.com+86 150 8234 1731

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026