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The Impact of Different Internal Limiting Membrane Management Techniques on Prognosis in Highly Myopic Macular Schisis Vitrectomy: A Randomized Controlled Study

The Impact of Different Internal Limiting Membrane Management Techniques on Prognosis in Highly Myopic Macular Schisis Vitrectomy: A Randomized Controlled Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097559
Enrollment
Unknown
Registered
2025-02-20
Start date
2025-02-24
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Highly Myopic Macular Schisis

Interventions

Control Group:Fovea-Sparing Internal Limiting Membrane Peeling
Experimental Group:Fovea-Sparing Internal Limiting Membrane Peeling Combined with ILM Inversion and Flap Technique

Sponsors

Eye Hospital Affiliated to Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with highly myopic macular schisis at our hospital and determined to require surgical treatment during outpatient visits; 2. Patients aged over 18 years.

Exclusion criteria

Exclusion criteria: 1. Patients with a full-thickness macular hole; 2. Patients with other retinal diseases, such as age-related macular degeneration, glaucoma, diabetic retinopathy, retinal detachment, etc.; 3. History of previous intraocular surgery; 4. Use of silicone oil tamponade during surgery.

Design outcomes

Primary

MeasureTime frame
The incidence of full-thickness macular hole within 3 months postoperatively.;

Secondary

MeasureTime frame
Postoperative Best-Corrected Visual Acuity (BCVA);Closure rate of the schisis cavity (with a reduction in area of more than 80%).;Change in central foveal thickness;

Countries

China

Contacts

Public ContactWu Ronghan

Eye Hospital Affiliated to Wenzhou Medical University

wuronghan@wmu.edu.cn+86 136 2577 2422

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026