Diabetes
Conditions
Interventions
Regular diet group:A balanced diet
Low carb diet group:Low carb diet plan
Precision low GI diet group:Develop personalized and precise low GI diet plan based on CGM data
Sponsors
Children's Hospital, Zhejiang University School of Medicine, National Clinical Research
Eligibility
Sex/Gender
All
Age
10 Years to 18 Years
Inclusion criteria
Inclusion criteria: (1)10~18 years (2)According to the American Diabetes Association (ADA) guidelines, meeting the diagnostic criteria for prediabetes means, one or more of the following conditions: 1)5.6 mmol/L = FBG= 6.9 mmol/L; 2)7.8mmol/L = OGTT 2 hours glucose= 11.0 mmol/L; 3)5.7% = HbA1C= 6.4%.
Exclusion criteria
Exclusion criteria: Subjects will not be enrolled if they meet any of the following criteria: 1)Diagnosed diabetes (including type 1 diabetes, type 2 diabetes, and monogenic diabetes); 2)Hereditary obese children; 3)Serious medical (heart, liver, lung) diseases, malignant tumors; 4)Infectious disease (active stage) or receiving medication for acute disease; 5)Have used CGM currently or within the last 6 months; 6)People who can't cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reversal rate of prediabetes at 24 weeks; | — |
Secondary
| Measure | Time frame |
|---|---|
| The level of HbA1c at 24 weeks;Fasting blood glucose at 24 weeks;Oral glucose tolerance test' 2 hours blood glucose at 24weeks; | — |
Countries
China
Contacts
Public ContactJunfen Fu
Children's Hospital, Zhejiang University School of Medicine, National Clinical Research
Outcome results
None listed