Gastric cancer
Conditions
Interventions
Experimental group:Billroth II+Braun anastomosis
Control group:Billroth II anastomosis
Sponsors
Shanghai Changzheng Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-75, either male or female; 2. Gastric adenocarcinoma was confirmed by pathology; 3. The tumor was located in the middle and lower part of the stomach (the distance between the proximal end of the tumor and the cardiac was >5cm). 4. Laparoscopic radical distal gastrectomy, including laparoscopically assisted or total abdominal surgery, is expected to be performed; 5. The preoperative clinical stage was cT1-4aN0-3M0, or the clinical stage was ycT1-4aN0-3M0 after neoadjuvant therapy; 6. ECOG physical strength score 0 or 1 before operation; 7. Preoperative ASA score was I-III; 8. Be able to complete the EORTC questionnaire.
Exclusion criteria
Exclusion criteria: 1. There are clear anesthesia or surgical contraindications; 2. Gastric stump cancer or a history of gastric surgery; 3. There is insufficiency of critical organs, which cannot tolerate surgery; 4. Advanced tumor, surgery for palliative purpose; 5. Gastric cancer complications (bleeding, perforation, obstruction) requiring emergency surgery; 6. Robotic platform surgery or open surgery; 7. Concurrent or previous history of other malignant tumors; 8. Pregnant or lactating women; 9. Those who suffer from mental illness and cannot cooperate with treatment; 10. History of unstable angina pectoris or myocardial infarction within 6 months; 11. History of cerebral infarction or cerebral hemorrhage within 6 months; 12. A history of continuous systemic corticosteroid therapy within 1 month; 13. Concurrent surgical treatment for other diseases is required; 14. Those who refuse to sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Life Questionnaire (QLQ-STO22) score for patients with gastric cancer; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of reflux gastritis;Intraoperative blood loss;Total operation time;The time length of digestive tract reconstruction;Post-operative hospital stay;Hospitalization expenses;Incidence of anastomotic leakage;Incidence of anastomotic bleeding;Incidence of bowel obstruction;Incidence of duodenal stump leakage;Hemoglobin level;Serum total protein level;Serum albumin level;Body mass index; | — |
Countries
China
Contacts
Public ContactXin Zhang
Shanghai Changzheng Hospital
Outcome results
None listed