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Clinical efficacy and mechanism of Naoxintong capsule in the treatment of hyperlipidemia based on intestinal flora and metabolomics

Clinical efficacy and mechanism of Naoxintong capsule in the treatment of hyperlipidemia based on intestinal flora and metabolomics

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097533
Enrollment
Unknown
Registered
2025-02-20
Start date
2022-07-20
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperlipidemia

Interventions

experimental group:Naoxintong Capsule treatment
control group:Conventional treatment

Sponsors

Foshan Sanshui District People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. 18 years old =5.2mmol/L; 3. High triglyceride, TG>=1.7mmol/L; 4. Abnormal low density lipoprotein level, LDL-C>=3.4mmol/L; 5. Abnormal high density lipoprotein level, HDL-C< 1.0mmol /L; Any of the above five conditions can be met.

Exclusion criteria

Exclusion criteria: 1. Cardiac arrest, cardiopulmonary resuscitation, the latter; 2. Patients with serious blood system diseases (hemophilia, severe anemia, thrombocytopenic purpura, essential thrombocythemia); 3. Severe renal insufficiency (serum creatinine level >= 220umol/L); 4. Severe liver disease (cirrhosis or liver cancer), liver function impairment (serum alanine aminotransferase/aspartate aminotransferase > 2 times the upper limit of normal); 5. Allergic to Naoxintong capsule.

Design outcomes

Primary

MeasureTime frame
Therapeutic effect;

Secondary

MeasureTime frame
Intestinal flora changes;Lipid metabolism;Hepatic and renal function;Blood routine examination;Routine urine examination;Stool routine examination;Coagulation function;

Countries

China

Contacts

Public ContactLiao XuXing

Foshan Sanshui District People's Hospital

drliao.@126.com+86 136 6720 2658

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026