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Study on the Mediating Role of Triglyceride-Glucose Index in the Relationship between Obstructive Sleep Apnea and Non-alcoholic Fatty Liver Disease

Study on the Mediating Role of Triglyceride-Glucose Index in the Relationship between Obstructive Sleep Apnea and Non-alcoholic Fatty Liver Disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500097521
Enrollment
Unknown
Registered
2025-02-20
Start date
2025-02-20
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea

Interventions

Observation group:None

Sponsors

Fifth Affiliated Hospital, Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 30 years old, no gender restriction; 2.According to the criteria of the International Classification of Sleep Disorders (Third Edition), OSA was diagnosed using nocturnal polysomnography, and NAFLD was diagnosed using abdominal ultrasonography.

Exclusion criteria

Exclusion criteria: 1.Individuals with significant alcohol consumption (males > 30 grams/day, females > 20 grams/day); 2.Individuals with incomplete information on abdominal ultrasound, fasting blood glucose, fasting triglycerides, or covariates (age, gender, BMI, smoking status, hypertension, and diabetes).

Design outcomes

Primary

MeasureTime frame
Mediating effect of the Triglyceride-Glucose Index between OSA and nonalcoholic fatty liver disease;—

Countries

China

Contacts

Public ContactHaiyu Hong

Fifth Affiliated Hospital, Sun Yat-Sen University

honghy@sysu.edu.cn+86 756 2528832

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026