Laparoscopic cholecystectomy
Conditions
Interventions
Cyprofol group:During anesthesia induction, a loading dose of Cyprofol is administered at 0.5–0.6 mg/kg, followed by a continuous intravenous infusion of Cyprofol (maintaining BIS in the range of 40-6
Propofol group:During anesthesia induction, a loading dose of Propofol is administered at 1.5–2.5 mg/kg, followed by a continuous intravenous infusion of Propofol (maintaining BIS in the range of 40-6
Sponsors
First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18-65 years; 2) Daytime surgery; 3) Scheduled to undergo laparoscopic cholecystectomy under general anesthesia; 4) Agree to participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Refusal to participate in this study; 2) ASA III. level or above; 3) BMI29.9kg/m^2; 4) History of chronic analgesic or sedative drug use including benzodiazepines, alcohol abuse, allergy to cyclopofol or propofol; 5) history of insomnia; 6) MMSE score of severe cognitive impairment before operation=180mmHg; 10) Surgery within the past 3 months; Participation in other research studies within the past 30 days; 11) Patients who have taken hormones or other immunosuppressive drugs for more than 10 days in the past 6 months or have a history of adrenal suppression or immune system disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15, QoR-15; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative hospital complications;Response time to verbal commands and extubation time;PACU stay time;Patient self-reported pain, anesthesia comfort, and satisfaction.; | — |
Countries
China
Contacts
Public ContactYao Lu
First Affiliated Hospital of Anhui Medical University
Outcome results
None listed