Autism spectrum disorder,Dravet syndrome,Self-limited epilepsy with centrotemporal spikes
Conditions
Interventions
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1.ASD (1) Age range =18 years old; (2) Clinically diagnosed with autism, the diagnosis of autism meets the Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-V criteria); (3) No previous history of head trauma; (4) neurological disorders with no known cause, such as epilepsy; (5) The duration of EEG data is not less than 20 minutes. 2.SeLECTS (1) Age range =18 years old; (2) Meet the diagnostic criteria of self-limited epilepsy with central temporal spines; (3) The duration of EEG data is not less than 20 minutes. 3.Dravet syndrome (1) Age range =18 years old; (2) Meet the diagnostic criteria for Dravet syndrome; (3) The duration of EEG data is not less than 20 minutes.
Exclusion criteria
Exclusion criteria: 1.ASD (1) Incomplete medical history data, lack of scale evaluation results or EEG data and other important medical history data; (2) visual or hearing impairment, acute encephalopathy or other serious physical disease; (3) have taken anti-seizure drugs or other nervous system and mental illness related drugs. 2.SeLECTS (1) Incomplete medical history data, lack of scale evaluation results or EEG data and other important medical history data; (2) EEG data did not meet the requirements. 3.Dravet syndrome (1) Incomplete medical history data, lack of scale evaluation results or EEG data and other important medical history data; (2) EEG data did not meet the requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain age; | — |
Secondary
| Measure | Time frame |
|---|---|
| Griffith Developmental Scale - Chinese edition;Wechsler Intelligence Scale for Children - fourth edition;childhood autism rating scale;Vineland Adaptive Behavior Scales,Third Edition;Social Responsiveness Scale,Second Edition;Autism Behavior Checklist;The National Hospital Seizure Severity Scale;Clinical Global Impression;Quality of Life in Children with Epilepsy-16; | — |
Countries
China
Contacts
Public ContactTaoyun Ji
Peking University First Hospital
Outcome results
None listed