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Comparison of the anesthetic effects of oliceridine-propofol and fentanyl-propofol anesthetic regimens for painless abortion

Comparison of the anesthetic effects of oliceridine-propofol and fentanyl-propofol anesthetic regimens for painless abortion

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097499
Enrollment
Unknown
Registered
2025-02-19
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

painless abortion

Interventions

Fentanyl group (P group):Fentanyl was used for induction of anesthesia
Low dose olicerdine group (L group):Low-dose olicerdine for induction of anesthesia
Medium dose olicerdine group (M group):Medium-dose olicerdine for induction of anesthesia
Medium dose olicerdine group (H group):High-dose olicerdine for induction of anesthesia

Sponsors

Dazhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age >=20 years old; voluntary painless abortion; conscious, with normal communication ability; American Society of Anesthesiologists (ASA) classification ? ~ ?; signed informed consent and postoperative analgesia consent form

Exclusion criteria

Exclusion criteria: Presence of psychiatric disorders and verbal communication disorders; presence of severe hepatic or renal insufficiency that may affect drug metabolism; history of opioid allergy; history of chronic pain, chronic opioid therapy or psychotropic medications; comorbid respiratory disease; incomplete clinical information; comorbid malignancy.

Design outcomes

Primary

MeasureTime frame
Mean Arterial Pressure;Heart rate;

Secondary

MeasureTime frame
SpO2;Respiratory rate;Time to loss of consciousness;Awake time;Incidence of injection pain;Total propofol dosage;Additional amount of propofol;Time of first propofol addition;Incidence of postoperative pain;Incidence of adverse reactions;

Countries

China

Contacts

Public ContactXuping Hu

Dazhou Central Hospital

645321906@qq.com+86 177 2516 6326

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026