Hyperuricemia
Conditions
Interventions
Uric acid monitoring group:On a fixed day a week, patients used Jackjet uric acid meter + 60 test strips to measure blood uric acid on an empty stomach in the morning, 2 hours ± 15min and 11pm±30min a
Non-uric acid monitoring group:None
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Male aged 18-65; 2. Patients diagnosed with hyperuricemia refer to the fasting test of blood uric acid > 420µmol/L (7mg/dl) twice on the same day under normal purine diet 3. As judged by the physician, it is currently necessary to use febuxostat 40mg once a day to start regular uric acid-lowering drug treatment.
Exclusion criteria
Exclusion criteria: 1. Use of drugs that may affect uric acid within 2 weeks before enrollment, including: benzbromarone, allopurinol, febuxostat, etc.; 2. Severe hepatic insufficiency or kidney disease (AST or ALT > 3 times the upper limit of normal, or eGFR <30ml/min/1.73m2); 3. If other drugs are used in combination, the drug dose should be kept stable for three months before enrollment; 4. Unable to cooperate with regular self-monitoring of uric acid.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Uric acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient medication adherence;How often doctors adjust their medication regimens;Frequency of gout attacks;Change in nail uric acid content at 12 weeks from baseline ; | — |
Countries
China
Contacts
Public ContactHaibing Chen
Shanghai Tenth People's Hospital
Outcome results
None listed