Non-small cell lung cancer
Conditions
Interventions
Observational group:None
Sponsors
Beijing Hostipal
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Signed informed consent, age > 18 years and < 90 years; (2) Pathology confirmed NSCLC, according to the 8th edition of the International Association for the study of Lung Cancer TNM staging for stage I NSCLC; (3) The patient's Eastern Cooperative Oncology Group performance status (ECoG PS) score was 0-3 points; (4) Multi disciplinary treatment (MDT) was used to evaluate patients who could not or refused surgical resection; (5) The estimated survival is more than 3 months; (6) During the treatment process, provide the clinical pathological data and imaging data required by the research process, cooperate with the follow-up and collect the blood of the clinical efficacy evaluation node, and agree to use the test data for subsequent research and product development.
Exclusion criteria
Exclusion criteria: (1) Suffering from other malignant tumors or severe multiple organ dysfunction; (2) After surgery, they received other treatments, such as chemotherapy, radiotherapy, targeted therapy, immunotherapy, etc; (3) The estimated survival time is less than 3 months; (4) Unable to accept or provide imaging and other specified efficacy evaluation methods.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ctDNA clearance under comprehensive minimally invasive radical surgery treatment;the relationship between ctDNA monitoring and tumor recurrence;Analyzing the value of MRD technology in patients with NSCLC under comprehensive minimally invasive radical surgery treatment in conjunction with clinical data; | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparative analysis of the specificity and sensitivity of ctDNA and imaging CT tests and serum tumor markers;MRD positivity predicts recurrence in advance of clinical confirmation of recurrence;2-year OS (Overall Survival); | — |
Countries
China
Contacts
Public ContactXiaoguang Li
Beijing Hostipal
Outcome results
None listed