labor analgesia
Conditions
Interventions
Group S:Saline 5 ml was given intravenously and epidural anesthesia was administered after 10 minutes.
Group D1:0.1 µg/kg nalmefene 5 ml i.v. was given and epidural anesthesia was administered after 10 minutes.
Group D2:0.2 µg/kg nalmefene 5 ml i.v. was given and epidural anesthesia was administered after 10 minutes.
Sponsors
Yuhuangding Hospital
Eligibility
Sex/Gender
Female
Age
24 Years to 36 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1) complete medical history; (2) age 24-36 years old; (3) full-term, singleton, term primigravida; (4) ASA grading of grade I-II; (5) normal pelvic measurements, eligible for vaginal trial of labor; and (6) informed consent of the patient and her family members and signing of an informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) contraindications related to labor and delivery; (2) contraindications to anesthesia; (3) severe pregnancy complications such as hypertension, heart disease, preeclampsia, and hepatic and renal insufficiency, etc.; (4) mental disorders; (5) any history of itch-related diseases or pruritus before labor analgesia; (6) nausea and vomiting before labor analgesia; (7) opioid dependence or allergy to nalmefene; (8) nausea and vomiting before labor analgesia. or nalmefene allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pruritic; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea and vomiting;Pain scores;Total Sufentanil dosage;Vital signs;Mother and child ending;Maternal satisfaction; | — |
Countries
China
Contacts
Public ContactJiang Aihua
Yantai Yuhuangding Hospital
Outcome results
None listed