Depressive disorder
Conditions
Interventions
Control group:Conventional treatment: Includes (1) monotherapy with SSRIs, increasing the dose to an effective therapeutic dose as soon as the patient tolerates, and monitoring the plasma concentratio
Study Group A:Conventional treatment + moderate-intensity aerobic exercise therapy: Moderate aerobic exercise was added to the conventional antidepressant treatment for group B patients, at least 3 ti
Study Group B:Conventional treatment + moderate-intensity anaerobic exercise therapy: Patients were given moderate-intensity anaerobic exercise on the basis of conventional antidepressant treatment, a
Sponsors
The Second Affiliated Hospital of Xinxiang Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for mild to moderate depressive episodes of the International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10); (2) Age 18~60 years old, gender is not limited; (3) HAMD24 score of 20~35 points; (4) the use of single-medication monotherapy with first-line antidepressant selective serotonin reuptake inhibitors (SSRIs) according to expert recommendations for the treatment and management of depression (2022) and depression treatment guidelines; (5) No audio-visual impairment, able to cooperate with the completion of the scale survey.
Exclusion criteria
Exclusion criteria: (1) Electroconvulsive therapy is proposed; (2) Patients with cerebral organic diseases or obvious somatic diseases; (3) concomitant psychoactive substance dependence; (4) Pregnant, lactating and menopausal patients; (5) Those who have obvious suicidal tendencies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton's Depression Scale Score;Pittsburgh sleep quality index;Montreal Cognitive Assessment Scale Score; | — |
Countries
China
Contacts
Public ContactCong Liu
The Second Affiliated Hospital of Xinxiang Medical University
Outcome results
None listed