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Research on the interaction mechanism and intervention strategy between cognitive reserve and family environment of chemotherapy-related cognitive impairment in colorectal cancer patients

Research on the interaction mechanism and intervention strategy between cognitive reserve and family environment of chemotherapy-related cognitive impairment in colorectal cancer patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097456
Enrollment
Unknown
Registered
2025-02-19
Start date
2024-10-09
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Experimental Group of Colorectal Cancer Patients With Chemotherapy-Related Cognitive Impairment (Part III):The first draft of the chemotherapy-related cognitive impairment management protocol for colo

Sponsors

Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Part 1: (1) Those who are receiving chemotherapy at least 1-2 times; (2) Age>= 18 years old; (3) Able to complete the required research questionnaire independently or with the help of the investigator;(4) Those who are informed of the diagnosis and agree to accept the study. Part 2: (1) Medical staff: (1) More than 5 years of work experience in oncology; (2) Intermediate and above titles; (3) Sign the informed consent form and voluntarily participate in this study. (2) Patients: (1) Patients who have been clearly diagnosed with colorectal cancer according to the diagnostic criteria for colorectal cancer and have received chemotherapy for 1-2 times; (2) Age>= 18 years old; (3) be able to understand the content of the interview; (4) Informed consent to participate in this study

Exclusion criteria

Exclusion criteria: (1) Those with tumor recurrence, brain metastasis or multiple metastases; (2) Patients with severe systemic infection, or other serious physical diseases, such as limb dysfunction, ascites, anemia, liver and kidney damage, infection, and heart disease; (3) Patients with neurological diseases and traumatic brain injury; (4) Those with a family history of hereditary mental illness; (5) Those who use drugs that have an effect on cognitive function; (6) Those who have been clearly diagnosed with cognitive impairment ;(7) Those who have severe visual, auditory, or verbal communication impairments; (8) Long-term excessive alcohol consumption or drug dependence history; (9) are receiving hormone therapy; (10) Pregnant; (11) Those who receive protective medical care or other interventions; (12) Receiving hospice care. Part 2: 1. Medical staff: medical staff who rotate and study; 2. Patients: (1) Speech and communication disorders; (2) unable to cooperate with the interviewer; (3) Protectors of medical conditions; (4) Severe mental illness.

Design outcomes

Primary

MeasureTime frame
Subjective and objective cognitive function assessment;patient-reported outcomes;Cognitive reserves;Family environment;body composition;

Secondary

MeasureTime frame
Skin fold thickness;Body circumference measurement;Muscle strength measurements;

Countries

China

Contacts

Public ContactLiu Dun

Fujian Medical University

liudun2005@163.com+86 135 1406 9044

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026