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Effect of Neiyi Prescription on Dysmenorrhea and Related Factors in Patients with Endometriosis of Qi Stagnation and Stasis Toxin Type

Effect of Neiyi Prescription on Dysmenorrhea and Related Factors in Patients with Endometriosis of Qi Stagnation and Stasis Toxin Type

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097453
Enrollment
Unknown
Registered
2025-02-19
Start date
2024-10-15
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis

Interventions

Control group:On the 5th day of the menstrual cycle, Yousiming was taken orally once a day for 21 consecutive days.Continuous medication for 3 menstrual cycles
Treatment group:On the 5th day of the menstrual cycle, the Chinese medicine granules Neiyi Prescription were taken orally for 14 consecutive days, one dose per day, twice in the morning and evening. C

Sponsors

He'nan Province Hospital of TCM
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
21 Years to 45 Years

Inclusion criteria

Inclusion criteria: (1)patients who met the diagnostic criteria of Western medicine and TCM syndrome differentiation criteria ; (2)21 years old < age < 45 years old, regular menstrual cycle ( 21 ~ 35 days ) patients ; (3)patients with ectopic lesion diameter < 4cm ; (4)35U / ml < serum CA125 < 100U / ml ; (5)patients who volunteered to participate in this study and signed informed consent.

Exclusion criteria

Exclusion criteria: (1)patients with ovarian malignant tumor, uterine fibroids, adenomyosis and other organic lesions and primary dysmenorrhea ; (2)patients with other cardiovascular and cerebrovascular diseases, liver and kidney dysfunction and other diseases ; (3)patients preparing for pregnancy during lactation, pregnancy or in the near future ; (4)endometriosis patients who received hormone or other drugs within 3 months ; (5)Patients with contraindications or allergies to this test drug ; (6)Patients with any serious psychological abnormalities and mental disorders.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale;Chinese medicine syndrome scores;CA125;CA199;

Secondary

MeasureTime frame
HGB;Neutrophil-lymphocyte count ratio;HE4;VEGF;sVCAM-1/ sICAM-1;MMP-2;MMP-9;TIMP-1;

Countries

China

Contacts

Public ContactYanyan Zhou

He'nan Province Hospital of TCM

zyy19760803@126.com+86 135 2664 9210

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026