Genitourinary syndrome of menopause
Conditions
Interventions
GSM group:PRP injection
Estrogen group:Estriol cream
Sponsors
West China Second Hospital of Sichuan University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1. Patients with a confirmed clinical diagnosis of GSM, following the diagnostic criteria outlined in the Expert Consensus on Clinical Diagnosis and Treatment of Genitourinary Syndrome of Menopause (2020 edition). 2. No relevant treatment received in the past two weeks. 3. Complete clinical data and follow-up compliance. 4. Willingness to participate in the study and signed informed consent.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1. History of protein allergy. 2. Acute inflammatory phase of the genitourinary system. 3. Presence of hematologic disorders, immune dysfunction, or malignancies. 4. Pregnancy. 5. Severe systemic medical conditions affecting daily life (e.g., diagnosed severe cardiovascular diseases or immune system disorders). 6. Psychological or psychiatric disorders (e.g., depression) that prevent completion of follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chinese version of the Female Sexual Function Scale, CVFSFI;Vaginal Health Index (VHI);Pelvic floor muscle electromyography (EMG) ;Pad test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinary Incontinence Questionnaire short form, ICI-Q-SF;Patient subjective satisfaction questionnaire, PGI-I;Adverse events; | — |
Countries
China
Contacts
Public ContactWei Dongmei
West China Second University Hospital, Sichuan University
Outcome results
None listed