keratoconus
Conditions
Interventions
Cases group:Patients treated with optimized PTK combined with corneal collagen cross-linking for the treatment of keratoconus
Control Group:Patients treated with ordinary PTK combined with corneal collagen cross-linking.
Sponsors
Wuhan Aier Eye Hospital Hankou Branch
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Age>=18 years; The clinical diagnosis met the diagnostic criteria of the Chinese Keratoconus Expert Consensus (2019); Signed written informed consent; Able and willing to attend all trial evaluations and visits as directed.
Exclusion criteria
Exclusion criteria: Females who are pregnant, breastfeeding, or planning to become pregnant; Patients with acute infectious or non-infectious ocular disease of any anterior or posterior segment of the eye in either eye; History of previous intraocular or corneal surgery; Patients with thin corneal stromal thickness; Scar constitution, diabetes, collagen diseases, etc. may affect corneal wound healing; Systemic lupus erythematosus and rheumatoid arthritis, which can easily cause corneal lysis after surgery; Any condition that, in the opinion of the investigator, is not suitable to participate in this clinical trial. Research Methods:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Combined refraction;Scanning laser fundus examination;Eye A ultrasound;Eye B ultrasound;Confocal laser microscope corneal examination;Corneal topographic map;Corneal thickness examination;Corneal biomechanical examination; | — |
Countries
China
Contacts
Public ContactZengQingYan
Wuhan Aier Eye Hospital Hankou Branch
Outcome results
None listed