glaucoma
Conditions
Interventions
Discovery cohort – Postoperative scarring group:No intervention (analyzing metabolic differences between groups based on scarring outcomes)
Discovery cohort – Postoperative non-scarring group:No intervention (analyzing metabolic differences between groups based on scarring outcomes)
Validation cohort – Postoperative scarring group:No intervention (observational analysis of the relationship between target metabolites and postoperative scarring outcomes)
Validation cohort – Postoperative non-scarring group:No intervention (observational analysis of the relationship between target metabolites and postoperative scarring outcomes)
Sponsors
Changsha Aier Eye Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients clinically diagnosed with primary open-angle glaucoma or primary angle-closure glaucoma, whose intraocular pressure is poorly controlled with medication; 2. Patients who have undergone trabeculectomy or drainage tube implantation; 3. Patients who voluntarily participate in this study and provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1. History of ocular surgeries other than laser peripheral iridectomy; 2. Patients who did not receive mitomycin C during surgery; 3. Patients with no light perception; 4. Patients with other ocular diseases; 5. Patients with poor compliance who are unable to attend regular follow-up appointments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative scarring;Intraocular pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Filtration bleb morphology;Surgical success rate; | — |
Countries
China
Contacts
Public ContactPing Wu
Changsha Aier Eye Hospital
Outcome results
None listed