lung cancer
Conditions
Interventions
Group S:Local injection of 0.5 µg/kg dexmedetomidine around the stellate ganglion on the operated side
Group C:Saline control group
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 60-80 years; 2.18.5 < BMI < 24.0; 3. ASA classification I-III; 4. Scheduled for single-port thoracoscopic lobectomy
Exclusion criteria
Exclusion criteria: 1. Individuals with contraindications to regional puncture( infections around the puncture site, and coagulation disorders: such as PLT1.5); 2. Individuals who have experienced any cerebrovascular accidents within the past 3 months, such as stroke or transient ischemic attack (TIA); 3. Patients with language communication disorders or mental disorders; 4. Patients with severe bradycardia or II-III degree atrioventricular block; 5. Individuals with contraindications to experimental drugs and other anesthetics; 6. Identify patients with ipsilateral shoulder pain prior to surgery; 7.Identify patients with sleep disorder prior to surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of ipsilateral shoulder pain within 72h after surgery ;Intraoperative remifentanil consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of ipsilateral shoulder pain;Incidence of ipsilateral shoulder pain;Incidence of postoperative sleep disorders;Duration of ipsilateral shoulder pain;Duration of postoperative sleep disorders;Incision pain;Incidence of postoperative pulmonary complications (atelectasis, lung infection, etc.);Shoulder range of motion (in degrees);Hemodynamic indexes;Hospital stays;Incidence of adverse events (such as hypotension, arrhythmia, delirium, surgical site infection, etc.);Time to get out of bed;Use of analgesic pumps ;Plasma concentration of dexmedetomidine ; | — |
Countries
China
Contacts
Public ContactCheng Xinqi
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed