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Biological mechanisms and applied research on light therapy for patients with depression

Biological mechanisms and applied research on light therapy for patients with depression

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097364
Enrollment
Unknown
Registered
2025-02-18
Start date
2025-02-21
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depressive disorder

Interventions

Morning BLT group :bright light therapy
Morning MBLT group:Mid-bright light therapy
Morning placebo group:dim light therapy

Sponsors

Hefei Fourth People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1: Understand the study and sign the informed consent form 2: Meets ICD-10 diagnostic criteria for patients with monophasic depression 3: Primary school and above 4: Age 18-65

Exclusion criteria

Exclusion criteria: 1: Other severe mental disorders and organic brain damage, presence of agitation or delirium, substance abuse, alcohol or drug dependence and uncooperative; 2: Currently suffering from a serious and unstable physical illness, such as diabetes, thyroid disease, etc. 3: Pregnant or breastfeeding women, or those planning a pregnancy; 4: patient who cannot take medication as prescribed by a doctor; 5: Shift work currently exists; 6: Drugs affecting endogenous cortisol and glucose-lipid related medications in the month prior to enrollment; 7: Electroconvulsive therapy within 3 months.

Design outcomes

Primary

MeasureTime frame
Fasting blood glucose Triglycerides High-density lipoprotein Low-density lipoprotei;Hamilton Anxiety Scale scores;Hamilton Depression Scale;salivary cortisol;Salivary melatonin;Stroop Test;DST;Speech fluency test;PSG;Data of resting state;

Secondary

MeasureTime frame
EBPM TBPM;CPT-IP;

Countries

China

Contacts

Public ContactDaomin Zhu

Hefei Fourth People’s Hospital

daominzhu1977@126.com+86 186 5514 1567

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026