Schizophrenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Case group: (1) Relapsed patients aged 18~45 years old who have not taken medication for the first time or within 4 weeks, both men and women; (2) Mental score consistent with the International Classification and Diagnostic Criteria for Mental Disorders, 10th Edition (ICD-10).diagnostic criteria for schizome; (3) no history of electroconvulsive therapy; (4) Junior high school or above, good compliance, able to cooperate with the completion of cognitive function assessment; (5) Patients and their families have informed consent and signed the informed consent form. Control group: (1) no mental illness and no family history of mental illness; (2) Age 18~45 years old, male or female; (3) Junior high school or above, good compliance, able to cooperate with the completion of cognitive function assessment.
Exclusion criteria
Exclusion criteria: (1) Drug allergies; (2) the presence of severe organic diseases; (3) Those with metabolic diseases, immune, endocrine system related diseases or other systemic diseases; (4) Pregnant and lactating women; (5) Those who have been treated with antidepressant, anti-anxiety, antipsychotic drugs or mood stabilizers in the past 4 weeks; (6) BMI25; (7) Those who abuse psychoactive substances such as drugs or alcohol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FGF21 serum levels;FGF21 serum levels;FGF21 serum levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical indicators;Clinical symptoms of schizophrenia;Cognitive Function;Adverse reactions; | — |
Countries
China
Contacts
The Eighth People's Hospital of Zhengzhou City