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Comparison of the Effects of High-Flow Nasal Cannula Oxygen Therapy and Conventional Oxygen Therapy During Sedation for Flexible Bronchoscopy with Thermal Therapy: A Prospective Randomized Controlled Study

Comparison of the Effects of High-Flow Nasal Cannula Oxygen Therapy and Conventional Oxygen Therapy During Sedation for Flexible Bronchoscopy with Thermal Therapy: A Prospective Randomized Controlled Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097342
Enrollment
Unknown
Registered
2025-02-18
Start date
2024-12-24
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Airway stenosis

Interventions

High-flow oxygen therapy group:Oxygen therapy was given at a concentration of 29% and a flow rate of 60 L/min
Traditional oxygen therapy group:Oxygen therapy was given at a flow rate of 2 L/min

Sponsors

The First Affiliated Hospital of Naval Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Patients who intend to undergo flexible tracheoscopic thermal ablation (high-frequency electrical, laser, plasma) treatment in our hospital; (2) Age 18-75 years old; (3) ASA Levels 1-3; (4) The patient voluntarily participated and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Adults with the following conditions: 1) BMI greater than 30; 2) hypoxemia (oxygenation index less than 300); 3) accompanied by hypercapnia (arterial partial pressure of carbon dioxide greater than 45 mmHg); 4) 75% of patients had central airway stenosis confirmed by imaging before operation>; 2. Patients with HFNC contraindications; 3. Poorly controlled comorbidities or serious systemic diseases; 4. Patients with anticoagulant drugs and coagulation disorders; 5. Allergy to anesthetic drugs; 6. Have a history of alcohol or drug abuse; 7. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
Incidence of hypoxemia;

Secondary

MeasureTime frame
Pulse Oxygen Saturation, SpO2;Transcutaneous carbon dioxide tension, TcPCO2;Operation duration;

Countries

China

Contacts

Public ContactZhang Wei

The First Affiliated Hospital of Naval Medical University

zhangweismmu@126.com+86 138 1780 4080

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026