I. Occurrence of pulmonary complications within 7 days postoperatively (including any pleural effusion, pulmonary edema, pulmonary embolism, pneumonia, acute respiratory distress syndrome, bronchospasm, aspiration, pneumothorax. Mainly determined by the patient's discharge diagnosis and other medical documents) II. Oxygenation status: 1) Poor oxygen therapy effect: ? Decline in oxygen saturation
Conditions
Interventions
HFNC group:high-flow nasal cannula oxygen therapy, HFNC
COT group:conventional oxygen therapy, COT
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=18 years old, ASA assessed the patients with grade I to III under general anesthesia; 2. 28.0 kg/m^2<=BMI<35.0kg/m^2; 3.Volunteer to participate in the study and sign the informed consent;
Exclusion criteria
Exclusion criteria: 1.There are respiratory diseases that may require continuous oxygen therapy before surgery, such as COPD, pulmonary infection, pneumothorax, atelectasis, asthma, etc; 2.Patients with a history of mental disorders or inability to communicate; 3.HFNC contraindication: upper respiratory tract complete obstruction or nasal obstruction; Any history of nasal/facial defects that may prevent the use of HFNC or the mask; 4.There are electrical impedance tomography (EIT) monitoring contraindos: chest circumference >150cm and can not use the EIT belt; Implantation of a pacemaker, defibrillator or other device that may interfere with electrical impedance measurements; There are wounds or dressings in the EIT wearing area.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PaO2/FiO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic Blood Pressure (SBP);Heart rate (HR);Respiratory rate;Pulse oxygen saturation;Respiratory mechanics related indicators;Lung function assessment;Diastolic Blood Pressure (DBP);Mean Blood Pressure (MBP);Visual Analogue Scale assessment;Lung Ultrasound Score assessment (LUS score);the incidence of pulmonary complications within 7 days postoperatively;Richmond Agitation-Sedation Scale(RASS);visual analog scale(VAS);the incidence rate of acute respiratory system events during oxygen therapy;hospital stay duration;whether transferred to the ICU;the duration of ICU stay; | — |
Countries
China
Contacts
Public ContactWu Jing
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed