Heart Failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The patient is older than 18 years old; 2. The total number of visits of the patient is greater than 2 times; 3. The patient has a clear diagnosis of HF, New York Heart Association (NYHA) functional level II to IV, and NT-proBNP is higher than the critical value (the critical value range is selected according to the actual clinical situation); 4. Echocardiogram results in the previous first diagnosis and treatment record, and the LVEF is in the range of [41%-49%].
Exclusion criteria
Exclusion criteria: 1. Diagnosis of isolated right heart failure (Isolated right HF); 2. Significant pericardial constriction, major valvular heart disease or congenital heart disease (with clear indications for surgery) during the first diagnosis and treatment; 3. Have undergone heart transplantation; 4. The medical records are incomplete, or more than 20% of the information of most variables is missing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measure:Deterioration of heart failure(Emergency visit for HF requiring hospitalization or intravenous treatment due to worsening HF symptoms);Primary outcome measure:Composite outcome of cardiovascular death; | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference in LVEF between the initial observation time and the end of observation period;Non-cardiac death;New-onset symptomatic arrhythmias of various types;Thrombotic complications due to other causes;Severe adverse drug reactions; | — |
Countries
China
Contacts
The First Affiliated Hospital of Army Medical University