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Constructing a prognostic model for heart failure patients with mildly reduced ejection fraction based on machine learning algorithms.

Constructing a prognostic model for heart failure patients with mildly reduced ejection fraction based on machine learning algorithms.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500097328
Enrollment
Unknown
Registered
2025-02-17
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Failure

Interventions

Predictive model groups:None

Sponsors

The First Affiliated Hospital of Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. The patient is older than 18 years old; 2. The total number of visits of the patient is greater than 2 times; 3. The patient has a clear diagnosis of HF, New York Heart Association (NYHA) functional level II to IV, and NT-proBNP is higher than the critical value (the critical value range is selected according to the actual clinical situation); 4. Echocardiogram results in the previous first diagnosis and treatment record, and the LVEF is in the range of [41%-49%].

Exclusion criteria

Exclusion criteria: 1. Diagnosis of isolated right heart failure (Isolated right HF); 2. Significant pericardial constriction, major valvular heart disease or congenital heart disease (with clear indications for surgery) during the first diagnosis and treatment; 3. Have undergone heart transplantation; 4. The medical records are incomplete, or more than 20% of the information of most variables is missing.

Design outcomes

Primary

MeasureTime frame
Primary outcome measure:Deterioration of heart failure(Emergency visit for HF requiring hospitalization or intravenous treatment due to worsening HF symptoms);Primary outcome measure:Composite outcome of cardiovascular death;

Secondary

MeasureTime frame
Difference in LVEF between the initial observation time and the end of observation period;Non-cardiac death;New-onset symptomatic arrhythmias of various types;Thrombotic complications due to other causes;Severe adverse drug reactions;

Countries

China

Contacts

Public ContactJing Tao

The First Affiliated Hospital of Army Medical University

xnkjt@sohu.com+86 23 68772189

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026