Stage II/III colorectal cancer
Conditions
Interventions
Experimental group:During the period from 5 days postoperatively to 42 days before the second chemotherapy, the subjects followed a goal-directed nutritional support strategy for nutritional managemen
Control group:During the period of 5 days after surgery to 42 days before the second chemotherapy, participants followed a goal-directed nutritional support strategy for nutritional management, but th
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients with stage II/III CRC diagnosed by histology or cytology 5-7 days after colorectal cancer; (2) Age 18-80 years old (including boundary value), male or female and ethnic group; (3) Patients who need chemotherapy after surgery, and are currently in stable disease status and in good general physical condition; (4) Subjects who need nutritional therapy according to the judgment of the investigator; (5) Those who can tolerate enteral nutrition; (6) Expected survival >=3 months; (7) Those who voluntarily participate in clinical trials and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients who have undergone chemoradiotherapy in the past; (2) subjects who do not require artificial nutrition support; (3) There are diseases that seriously affect the digestion and absorption of the test products; (4) Subjects who are expected to not be able to take the trial product according to the regulations, and subjects who are not expected to reach the prescribed dosage as required, such as subjects who cannot be controlled after surgery and chemotherapy with severe nausea and vomiting; (5) Those who cannot tolerate enteral nutrition; (6) Known allergy to the ingredients contained in the products of the experimental group; (7) Participated in other interventional clinical trials (including drugs, nutritional preparations, medical devices, etc.) within 4 weeks before screening; (8) Other circumstances (such as pregnant or lactating women) that are considered by the investigator to be unsuitable for participating in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum albumin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body mass index;Prealbumin;Grip strength;C-reactive protein;Total lymphocyte count; | — |
Countries
China
Contacts
Public ContactLiyong Chen
Qilu Hospital of Shandong University
Outcome results
None listed