renal injury
Conditions
Interventions
Partial nephrectomy group:Routinely perform partial nephrectomy
Renal sympathetic denervation+partial nephrectomy group:The patient underwent renal sympathectomy concurrently with performing partial nephrectomy.
Sponsors
The Third Medical Center, Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Renal cancer patients who are candidates for nephron-sparing surgery; 2.Patients with an expected total warm ischemia time of over 20 minutes; 3.Patients who understand and voluntarily sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients who are not suitable for nephron-sparing surgery; 2.Patients who have undergone renal transplantation; 3.Patients with a solitary kidney; 4.Patients with recurrence after partial nephrectomy; 5.Patients with a short expected lifespan; 6.Patients for whom the physician does not recommend this treatment regimen due to other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative renal function of the operated kidney; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative overall renal function;Incidence rate of renal atrophy 24 months postoperatively (assessed by changes in renal cortical volume via enhanced CT); | — |
Countries
China
Contacts
Public ContactMa Xin
The Third Medical Center, Chinese PLA General Hospital
Outcome results
None listed