Obesity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Be between the ages of 11 and 17 years old, and meet one of the categories of normal weight, overweight, and obesity according to the health industry standard WS/T 5862018 of the People's Republic of China 2. Informed consent of parents and individuals 3.Stable weight (self-reported weight change <5 kg) within 90 days prior to the screening period
Exclusion criteria
Exclusion criteria: 1. Malnutrition 2. Secondary obesity, including endocrine and metabolic diseases (such as Cushing's syndrome, hypothyroidism, hypogonadism, polycystic ovary syndrome, etc.) 3. Have recently taken or are taking drugs that affect metabolism, such as glucocorticoids, prednisone, etc 4. Other diseases (tumors, trauma, fractures, convalescent from surgery, active diseases, etc.) 5. History of psychiatric disorders (such as schizophrenia, bipolar disorder, major depression, eating disorders, etc.). 6. Any condition that, in the opinion of the investigator, may endanger the safety of the individual
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall TDI score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Olfaction indicators;Body composition;Intrahepatic triglyceride content;Psychological status;Anthropometric and physical indicators;Other biomarkers;fMRI-related indicators of the brain;Proteomics;Genomics;Metabolomics;Lipidomics;Food preference;Physical fitness;Ophthalmology indexes;Fundus;Vision;Metagenomics;Cognitive function;Demographic surveys;Autonomic neuropathy;Clinical Biochemistry Tests;Phenomics; | — |
Countries
China
Contacts
Shanghai Sixth People's Hospital