Metabolic syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Obese patients with BMI>=30kg/m^2 and ages 18-65 years old who were proposed to undergoing bariatric surgery under elective general anesthesia were continuously enrolled in our study from December 2024 to December 2025.
Exclusion criteria
Exclusion criteria: (1) Patients unable to provide informed consent and communication difficulties before surgery; (2) Patients with severe heart, respiratory, kidney or liver disease and prolonged QT interval; (3) Allergic to any of the narcotic drugs to be studied; (4) There is a history of mental illness, depression, or long-term use of psychiatric drugs; (5) Premedication or preexisting medical conditions prior to surgery limit target assessment, including the use of antiemetics, opioids, or corticosteroids; (6) Severe gastroesophageal reflux; (7) Refused to enroll patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PONV grading;NVAS score;Postoperative antiemetic drug dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Apfel score;Postoperative adverse reaction; | — |
Countries
China
Contacts
The First Affiliated Hospital of Nanjing Medical University