Skip to content

Effect of droperidol on postoperative nausea and vomiting in patients undergoing bariatric surgery: a single-center, prospective, randomized controlled study

Effect of droperidol on postoperative nausea and vomiting in patients undergoing bariatric surgery: a single-center, prospective, randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097291
Enrollment
Unknown
Registered
2025-02-17
Start date
2025-02-17
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic syndrome

Interventions

Control group:The control group was given the same amount of normal saline.
The droperidol group:Intraoperative intravenous injection of 1 mg droperidol +4 mg droperidol combined with intravenous controlled analgesia.

Sponsors

The First Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Obese patients with BMI>=30kg/m^2 and ages 18-65 years old who were proposed to undergoing bariatric surgery under elective general anesthesia were continuously enrolled in our study from December 2024 to December 2025.

Exclusion criteria

Exclusion criteria: (1) Patients unable to provide informed consent and communication difficulties before surgery; (2) Patients with severe heart, respiratory, kidney or liver disease and prolonged QT interval; (3) Allergic to any of the narcotic drugs to be studied; (4) There is a history of mental illness, depression, or long-term use of psychiatric drugs; (5) Premedication or preexisting medical conditions prior to surgery limit target assessment, including the use of antiemetics, opioids, or corticosteroids; (6) Severe gastroesophageal reflux; (7) Refused to enroll patients.

Design outcomes

Primary

MeasureTime frame
PONV grading;NVAS score;Postoperative antiemetic drug dosage;

Secondary

MeasureTime frame
Apfel score;Postoperative adverse reaction;

Countries

China

Contacts

Public ContactHongquan Dong

The First Affiliated Hospital of Nanjing Medical University

donghongquan@jsph.org.cn+86 182 6263 6637

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026