Postoperative delirium
Conditions
Interventions
POD group :None
non-POD group:None
Sponsors
Department of Anaesthesiology, Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) patients =35 and <95 years of age; (2) preoperative cranial magnetic brain examination.
Exclusion criteria
Exclusion criteria: (1) Intracranial and extracranial vascular stenosis >=50%; (2) Have MRI contraindications or cannot tolerate MRI imaging; (3) Mental disorder or severe dementia before surgery, MMSE score < 10 points; (4) Preoperative MRI showed the presence of other brain diseases (such as brain tumor, stroke, multiple sclerosis, central nervous system infection and sequelae); (5) Have other diseases that may lead to dementia; (6) Preoperative MRI showed hippocampal and temporal lobe atrophy exceeding grade II, indicating that Alzheimer's disease may occur; (7) Malignant tumors with poor prognosis such as pancreatic cancer, gallbladder cancer, and cholangiocarcinoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| White Matter Hyperintensity Total Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Periventricular Hyperintensity score;Deep White Matter Hyperintensity Score;Cerebral atrophy score;Number and distribution of lacunar infarcts ;Number and distribution of microhaemorrhagic foci ;Basal Ganglia Perivascular Spaces;White Matter Perivascular Spaces;Cerebral Small Vessel Disease Total Load Score; | — |
Countries
China
Contacts
Public ContactZhengqian Li
Peking University Third Hospital
Outcome results
None listed