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Clinical study of disorders of amino acid metabolism in acute respiratory distress syndrome

Clinical study of disorders of amino acid metabolism in acute respiratory distress syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500097287
Enrollment
Unknown
Registered
2025-02-17
Start date
2025-02-20
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute respiratory distress syndrome (ARDS)

Interventions

Case group:None
Control group:None

Sponsors

The First Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Case group:1) critically ill patients between the ages of 18-90 years admitted to the ICU who meet criteria for sepsis or septic shock; and 2) patients undergoing mechanical ventilation (invasive or non-invasive) for hypoxic respiratory failure, who also meet diagnostic criteria for ARDS. Twenty healthy people were matched according to age and sex as healthy control groups.

Exclusion criteria

Exclusion criteria: 1) Near-death status or death within 48 hours of enrolment; 2) pregnant and puerperal patients; 3) immunologically abnormal patients; and 4) presence of chronic respiratory failure.

Design outcomes

Primary

MeasureTime frame
phenylalanine;Phenacetoglutamine;tyrosine;Phenylacetic acid;Citrulline;I-FABP;—

Secondary

MeasureTime frame
Lipolyaccharide;D-lactic acid;—

Countries

China

Contacts

Public ContactZhang Jing

The First Hospital of Jilin University

zhangjing0210@jlu.edu.cn+86 136 1071 1477

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026