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Effects of tACS on working memory based on fNIRS

Effects of tACS on working memory based on fNIRS

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097278
Enrollment
Unknown
Registered
2025-02-17
Start date
2025-02-28
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Group ?-tACS:The stimulation frequency was 6Hz, the stimulation intensity was 1mA, and the stimulation time was 20min, and the stimulation frequency was 40Hz, the stimulation intensity was 1mA, and th
Group ?-tACS:The stimulation frequency was 40Hz, the stimulation intensity was 1mA, and the stimulation time was 20min, and after one week of elution, the stimulation frequency was 6Hz, the stimulatio
Group Sham:Sham

Sponsors

Xuzhou Rehabilitation Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. Age and gender: 18 - 30 years old, male or female; 2. Be healthy adults without a history of neurological or mental illness; 3. There should be certain requirements for the baseline level of working memory. For example, participants are determined to have normal cognitive function through specific cognitive tests; 4. Participants must be able to understand the nature of the study and voluntarily sign the informed consent form; 5. According to the needs of the study, right - handed participants are required; 6. If the task involves language processing, participants should have native - language - level language ability.

Exclusion criteria

Exclusion criteria: 1. Individuals with a significant history of neurological diseases should be excluded, such as epilepsy, stroke, brain injury, etc; 2. Those with a serious history of mental illness, such as schizophrenia, bipolar disorder, etc., should be excluded; 3. Individuals with a history of drug or alcohol dependence; 4. Exclude individuals with hearing loss; 5. Individuals with intracranial metal implants or other implants that may interact with tACS should be excluded; 6. Considering the potential impact of tACS on fetuses or infants, pregnant or breastfeeding women should be excluded; 7. Individuals with severe skin conditions, such as eczema or open wounds, that may affect the placement of tACS electrodes should be excluded; 8. Those with other medical conditions that may affect the research results, such as heart disease, uncontrolled diabetes, etc.

Design outcomes

Primary

MeasureTime frame
Visual Working Memory Capacity, VWM;

Secondary

MeasureTime frame
digit span test,DST;Beta values, peak values, and average values in task-state assessment of near-infrared spectroscopy (fNIRS);Reaction time (ms) and accuracy (%) of N - back.;

Countries

China

Contacts

Public ContactZunke Gong

Xuzhou Rehabilitation Hospital

gongzunke@163.com+86 189 5217 2330

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026