protrusion of lumbar intervertebral disc
Conditions
Interventions
Sitting nasal spray group:Dexmedetomidine nasal spray was administered through the nose while seated
Prone position nasal spray group:Dexmedetomidine nasal spray was administered in a prone position
Buccal mucosa administration group in prone position:Dexmedetomidine nasal spray 100ug was administered via buccal mucosa in prone position
Sponsors
Hebei General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients undergoing foraminoscopy under anesthesia in Hebei Provincial People's Hospital were male and female, aged 18-65 years old, with clear consciousness and capacity for civil conduct, and no contraindications to surgery and anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients with severe rhinitis and nasal malformations; Patients with mouth ulcers. 2. Patients with myocardial infarction, unstable angina pectoris, severe arrhythmia, and cardiac insufficiency. 3. Patients with severe asthma, severe emphysema, severe bronchitis, and severe chronic obstructive pulmonary disease. 4. Patients with severe liver insufficiency. 5. Patients allergic to dexmedetomidine and its ingredients 6. Patients refuse. 7. Patients with serious adverse reactions occurred during the operation, terminating the operation or changing the anesthesia method.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The depth of anesthesia and sedation;Modified Observational Assessment of Alertness and Sedation, MOAA/S;Ramsay;visual analogue scale;heart rate variability; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;heart rate;saturation of pulse oximetry;perfusion index;adverse reaction; | — |
Countries
China
Contacts
Public ContactZhang Dong
Hebei General Hospital
Outcome results
None listed