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Construction and validation of a bladder cancer efficacy prediction system based on multimodal and multi-omics features

Construction and validation of a bladder cancer efficacy prediction system based on multimodal and multi-omics features

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500097266
Enrollment
Unknown
Registered
2025-02-17
Start date
2025-02-22
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder cancer

Interventions

Transurethral cystectomy for tumours group:None
Radical cystectomy group:None
Comprehensive bladder preservation therapy group:None

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients must be >= 18 years of age; 2. Patients with pathologically diagnosed malignant tumours of the bladder; 3. Patients who have received a standardised bladder cancer treatment protocol; 4. Patients with 3 or more years of follow-up information; 5. The major organs (heart, liver, lungs, kidneys) function is basically normal, PS score: 0-2; 6. Patients must have comprehensive clinical data: (1) Imaging data: including CTU or MRI. (2) Pathological data: including full-field images of tissue sections and pathology reports. (3) Clinical data: including basic patient information (age, gender), medical history, treatment regimen, assessment of efficacy (e.g., RECIST criteria), and record of adverse reactions.

Exclusion criteria

Exclusion criteria: 1. Exclude patients with concurrent history of other malignancies; 2. Exclude patients who have recently received other experimental treatments; 3. Exclude patients with serious comorbidities (e.g., heart disease, liver or kidney insufficiency, etc.) that may affect the outcome of treatment; 4. Exclude patients with all missing imaging data or pathological data or poor image quality.

Design outcomes

Primary

MeasureTime frame
Area under curve;

Secondary

MeasureTime frame
Recurrence free survival;Progression-free survival;Overall survival;

Countries

China

Contacts

Public ContactHaitao Liu

Shanghai General Hospital

doctorlht69@163.com+86 153 0165 5608

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026