Stroke
Conditions
Interventions
Control Group:Conventional rehabilitation training
VR Group:Receive virtual reality therapy in addition to conventional rehabilitation training
Saebo Group:Receive treatment by wearing a dynamic wrist-hand orthosis in addition to conventional rehabilitation training.
Virtual reality combined with dynamic wrist-hand orthosis set:Receive treatment by wearing a dynamic wrist-hand orthosis while simultaneously undergoing virtual reality therapy in addition to conventi
Sponsors
Huashan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. The first onset of the disease, meeting the relevant diagnostic criteria of the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018, and confirmed by CT or MRI of the brain, and suggesting unilateral lesions; 2. Age 18~70 years old, male or female, left and right hands are not limited; 3. The range of motion of the upper limb joint meets the following conditions: the active flexion and extension, abduction, and external rotation > of the shoulder joint on the affected side = 45°, the extension > of the elbow joint on the affected side from the full flexion position = 20°, and the pronation and supination of the forearm on the affected side >=45°; Active dorsal extension of the wrist joint on the affected side >=20°, and extension of the metacarpophalangeal joint and any two interphalangeal joints of the finger >=10°; The abduction > of the thumb = 10°, and the action can be repeated 3 times within 1min. 4. Have a certain desire for recovery and family support; 5. The course of the disease < 6 months.
Exclusion criteria
Exclusion criteria: 1. History of previous stroke; 2. Contraindications to neuroelectrophysiological and near-infrared brain functional imaging assessment: epidermal damage, fever, history of tumor, wearing a pacemaker, intracranial metal implants and other metal implants in the body or skull defects, epilepsy patients, pregnant or lactating women, or women of childbearing age who do not take reliable contraceptive measures, etc.; 3. Severe systemic diseases that cannot participate in the study: those with severe respiratory, heart, liver, kidney, endocrine and hematopoietic diseases, such as congestive heart failure, arrhythmia, and hypertension that cannot be controlled; 4. Obvious limb disability or other diseases that affect the movement of upper limbs: severe infection of upper limbs, contractures, joint surgery, amputation, fractures, rheumatism or rheumatoid arthritis; 5. Those who have severe cognitive, speech, vision, hearing impairment (such as deaf-mute) or mental disorders that affect examination and treatment; 6. Patients who have recently participated in other clinical trials; 7. Upper extremity Brunnstrom stage =3 grade.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wolf Motor Function Scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Arm Movement Survey Scale Score;Triple spasticity scale score;Hamilton Anxiety Scale score;Hamilton Depression Rating Scale score;sEMG;MEP;fNIRS; | — |
Countries
China
Contacts
Public ContactSonghua Huang
Huashan Hospital Affiliated to Fudan University
Outcome results
None listed