None
Conditions
Interventions
VT6:Each patient underwent mechanical ventilation at 3 tidal volume levels in random order, and the respiratory mechanical indexes of each tidal volume level were measured 5 minutes after the respirat
VT8:Each patient underwent mechanical ventilation at 3 tidal volume levels in random order, and the respiratory mechanical indexes of each tidal volume level were measured 5 minutes after the respirat
VT10:Each patient underwent mechanical ventilation at 3 tidal volume levels in random order, and the respiratory mechanical indexes of each tidal volume level were measured 5 minutes after the respira
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age over 18 years old; 2.ASA class I-III; 3.BMI between 18kg/m2 and 30kg/m2; 4.Scheduled for abdominal surgery; 5.Informed and willing to participate in the trial, and willing to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.History of severe lung diseases, such as chronic obstructive pulmonary disease, severe asthma, thoracic and spinal malformations, pleural effusion, pneumothorax and giant bulla, pulmonary surgery and other diseases affecting respiratory compliance 2.Severe cardiac, hepatic, renal, or hematologic disorders; 3.Central nervous system disorders impairing respiratory function; 4.Contraindications for PEEP use: intracranial hypertension, bronchopleural fistula, hypovolemic shock, etc.; 5.Participation in other clinical studies within the last 3 months; 6.Patients who refuse to participate in the trial or cannot cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mechanical power; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mechanical ventilation parameter;Arterial blood gas;Postoperative pulmonary complications; | — |
Countries
China
Contacts
Public ContactLijian Chen
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed