Pulmonary nodule
Conditions
Interventions
Test group 1 (5mg dexamethasone group):Intercostal nerve block was given under direct thoracoscopic vision before chest closure. The block site was the surgical incision and the upper and lower interc
Experimental group 2 (10mg dexamethasone group):Intercostal nerve block was given under direct thoracoscopic vision before chest closure. The block site was the surgical incision and the upper and low
Sponsors
The affiliated yongchuan hospital of chongqing medical university
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing single-port thoracoscopic lung surgery under general anesthesia at the elective stage 2. ASA grade I-III, 18~75 years old, body mass index (BMI) 18-28kg/m^2 3. Patients are aware of the content of the study and express their willingness to participate in and cooperate with the research work
Exclusion criteria
Exclusion criteria: 1. Patients with skin or deep tissue infection at the puncture site, patients with severe thoracic deformity 2. Patients with a history of allergy to local anesthetics and adrenocorticosteroids 3. Contraindications to dexamethasone (peptic ulcer, systemic infection, glaucoma, active varicella/herpes infection, diabetes mellitus with multiple complications) 4. Patients with coagulation dysfunction or receiving anticoagulant therapy 5. Patients with a history of neurological and psychiatric diseases or who are unable to use VAS to provide pain scores 6. Patients with hepatic and renal insufficiency 7. Patients with chronic opioid use 8. Patients admitted to ICU after surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of analgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-15 score;Opioid consumption 24h/48h after surgery;VAS rest/cough pain score and hemodynamic parameters;Intraoperative opioid consumption and duration of surgery;Time of chest drainage tube removal and length of hospital stay;The incidence of postoperative complications (nausea and vomiting; Itching; Respiratory depression; Pneumothorax; Local hemorrhage and hematoma; Postoperative systemic or wound infection, injury Delayed healing of mouth); | — |
Countries
China
Contacts
Public ContactMingqing Peng/Xiangwei Zhou
The affiliated yongchuan hospital of chongqing medical university
Outcome results
None listed