Adolescent depression.
Conditions
Interventions
Experimental group:Pharmacotherapy: Sertraline (specification: 50mg per tablet, Pfizer Pharmaceuticals Ltd., lot number: )
Starting dose: 50mg/day
Dose adjustment: titration gradually, the target dose
Control group:Pharmacotherapy: Sertraline (specification: 50mg per tablet, Pfizer Pharmaceuticals Ltd., lot number: )
Starting dose: 50mg/day
Dose adjustment: titration gradually, the target dose is 5
Sponsors
Kangci Hospital of Jiaxing City
Eligibility
Sex/Gender
All
Age
13 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1. Age 13-17 years old; 2. Have primary school education level or above; 3. Diagnosed by two psychiatrists who meet the DSM-5 diagnostic criteria for depression; 4. Meet the DSM-5 diagnostic criteria for non-suicidal self-injury; 5. The number of self-injuries within 1 month before enrollment is not zero; 6. No family history of mental illness; 7. Informed consent of patients and guardians.
Exclusion criteria
Exclusion criteria: 1. Comorbid with other organic diseases; 2. The patient has psychotic symptoms; 3. Suicidal thoughts within 1 month within two weeks prior to enrollment; 4. Have a history of substance abuse; 5. Suffering from severe cardiovascular disease; 6. History of epilepsy or mental retardation; 7. Metal implants (e.g., cardiac stents, implantable electronic devices, etc.) in the body.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale score;Depression Scale score in children; | — |
Secondary
| Measure | Time frame |
|---|---|
| Internet Addiction Scale score;Ottawa Self-Injury Scale score in Chinese; | — |
Countries
China
Contacts
Public ContactQingfeng Wu
Kangci Hospital of Jiaxing City
Outcome results
None listed