Takayasu Arteritis
Conditions
Interventions
Endovascular intervention group for Takayasu arteritis:NA
Open surgery group for Takayasu arteritis:NA
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 100 Years
Inclusion criteria
Inclusion criteria: 1. Complies with the diagnostic criteria for Takayasu's arteritis established by the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) in 2022. 2. Ineffectiveness of medical treatment. 3. Indications for surgical intervention: (1) Imaging tests show severe stenosis (>70%) or occlusion of the aorta and its branches. (2) Refractory renovascular or aortic coarctation hypertension. (3) Manifestations of ischemia in organs such as the heart, brain, and limbs. (4) Aneurysmal changes in the aorta.
Exclusion criteria
Exclusion criteria: 1. Combined serious hematological and endocrine system lesions or combined tumors; 2. Combined serious heart, lung, liver, kidney and other important organs lesions, unable to tolerate anesthesia and surgery; 3. Subjects with acute or chronic infectious diseases (except tuberculosis); 4. Subjects with mental disorders or other reasons who are unable or unwilling to cooperate with the treatment; 5. Those who are pregnant before surgical intervention treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite perioperative complications;Target vascular patency rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life scores;Disease activity;Immunosuppressive drug application;Antihypertensive drug application;Dehydration drug application;blood pressure level;Recurrence/exacerbation of symptoms; | — |
Countries
China
Contacts
Public ContactLi Yongjun
Beijing Hospital
Outcome results
None listed