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Study on the anesthetic effect of oliceridine compounded with propofol for painless gastroscopy

Study on the anesthetic effect of oliceridine compounded with propofol for painless gastroscopy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097246
Enrollment
Unknown
Registered
2025-02-14
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Painless gastroscopy

Interventions

Control:Propofol combined with sufentanil for induction of anesthesia
Group L:Propofol combined with low-dose oliceridine for induction of anesthesia
Group M:Propofol combined with medium-dose oliceridine for induction of anaesthesia
Group H:Propofol combined with high-dose oliceridine for induction of anaesthesia

Sponsors

Dazhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1 ASA (American Society of Anesthesiologists) Physical status I to II; 2 Adults between the ages of 18-70, body mass index (BMI) is between 18 and 25; 3 The patient is mentally normal and can communicate normally; ?Signed informed consent.

Exclusion criteria

Exclusion criteria: (1) people with respiratory or circulatory disorders; (2) people who are allergic to the study drug; (3) people with coronary heart disease, tuberculosis, liver failure and other important organ diseases; (4) people with acute cardiovascular and cerebral vascular diseases; (5) people with malignant tumors; (6) pregnant or breastfeeding women or people who have a plan to have children in the near future.

Design outcomes

Primary

MeasureTime frame
MAP;Heart rate;SpO2;

Secondary

MeasureTime frame
respiratory rate;Discharge time;Awake time;Propofol dosage;Injection pain;Nausea and vomiting;Gastroscopy time;Amount of propofol addition;Timing of propofol addition;Bucking ;Motion of body;Dizziness;Drowsiness;

Countries

China

Contacts

Public ContactXuping Hu

Dazhou Central Hospital

645321906@qq.com+86 177 2516 6326

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026