Lung Surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients undergoing thoracoscopic partial lung resection under general anesthesia; 2.Age >= 18 years old, gender unlimited; 3.American Society of Anesthesiologists (ASA) grades I-IV; 4.Expected one-lung ventilation duration >= 60 min; 5.Voluntary subjects signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Serious lung diseases, such as chronic obstructive pulmonary disease (GOLD grade 3-4), severe asthma, thoracic and spinal malformations, pleural effusion, pneumothorax, and history of prior lung surgery that affect lung compliance; 2.Severe heart (NYHA Grade III or IV), liver (Child-Pugh 10-15 points), kidney (renal replacement therapy), hematopoietic system (leukemia) diseases; 3.Previous history of lung surgery; 4.History of upper respiratory tract infection within 2 weeks before surgery; 5.Participating in other clinical studies in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygenation index;Postoperative pulmonary complications severity grade;Postoperative pain VAS score;Postoperative surgical complications grade; | — |
Countries
China
Contacts
The First Affiliated Hospital of Anhui Medical University