Oligoasthenospermia
Conditions
Interventions
Intervention group:Oral administration of levocarnitine and modified Wuzi Yanzong Pill
Control group:Oral administration of levocarnitine
Sponsors
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Male
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Male participants aged between 20-45 years old; (2) The Western medicine diagnosis criteria refers to the fifth edition of the "Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction". Diagnosis is based on the average of three semen biochemical tests, with sperm density <=15 × 106spz/mL or total sperm count < 39 × 106spz, and the percentage of progressively motile sperm (PR, grade a + b) below 32%. (3) Participants who are willing and able to sign an informed consent form; (4) No other serious comorbidities, such as heart disease, liver disease, kidney disease, etc.
Exclusion criteria
Exclusion criteria: (1) Men under 22 years of age or over 35 years of age; (2) Have used any medication to treat oligoasthenospermia in the past 6 months; (3) Have other diseases or conditions that may affect the results of the study, such as diabetes, hypertension, heart disease, liver disease, kidney disease, etc.; (4) Have a severe history of drug allergies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sperm concentration;Sperm vitality;Follicle stimulating hormone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Successful planting;Clinical pregnancy;Ongoing pregnancy;Threatened abortion;Early abortion;Ectopic pregnancy;Multiple pregnancy; | — |
Countries
China
Contacts
Public ContactSun Zhengao
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed